The elicitation of broadly neutralizing antibodies (bNAbs) may very well be essential for a preventative HIV-1 vaccine, but this has not yet been achieved by immunization. showed limited evolution and failed to develop breadth. Thus, early viral escape at key antibody-virus contact sites selects for sublineages that can tolerate these changes, providing a new mechanism… Continue reading The elicitation of broadly neutralizing antibodies (bNAbs) may very well be