Heparin-induced thrombocytopenia (HIT) is usually a thrombotic complication of heparin therapy mediated by antibodies to complexes between platelet factor 4 (PF4) and heparin or cellular glycosaminoglycans. such as coronary bypass surgery, yet only 1% of patients develop clinical HIT (4, 8C10). The MK-8033 reason why only a subset of anti-PF4-heparin Abs is associated with HIT… Continue reading Heparin-induced thrombocytopenia (HIT) is usually a thrombotic complication of heparin therapy