Much continues to be learned about the structure, function, and production of IgM, since the antibody’s initial characterization. mice was the generation of mice deficient for secretory IgM (sIgM). This mouse strain was generated by germline deletion of the chain secretory exon [30]. OSI-930 In sIgM-deficient mice, IgM is usually expressed around the cell membrane… Continue reading Much continues to be learned about the structure, function, and production